Endocrine Abstracts

Introduction: Homocysteine is an intermediate sulfur amino acid in the metabolic pathways of cysteine production from methionine, which is increasingly involved in various pathological processes (arterial thrombosis, depression, schizophrenia, dementia). We are interested in the course of our work to study the variation of homocysteine levels in diabetic subjects with venous thrombosis.Materials and methods: This is an observational case-control study, c...

Introduction: Homocysteine is an intermediate sulfur amino acid in the metabolic pathways of cysteine production from methionine, which is increasingly involved in various pathological processes (arterial thrombosis, depression, schizophrenia, dementia). We are interested in the course of our work to study its implication on the lipid balance in patients with venous thrombosis.Materials and methods: This is an observational case-control study, comparing ...

Introduction: Cortisol level measurement is required in the diagnosis and management of adrenal, pituitary and hypothalamic pathologies.Aim: The aim of this study was to evaluate clinician’s practice in ordering cortisol test.Methods: A retrospective study concerning 63 cortisol requests data collected by the laboratory computer system (Health Lab) between January 2024 and February 2024. Only requests of 0800 hours plasma cort...

Introduction: Allgrove syndrome or Triple A (3A) syndrome is a rare autosomal recessive disease characterized by alacrima, esophageal achalasia and adrenocorticotropic hormone-resistant adrenal insufficiency.Observation: A 3-year-old and 9 months patient, from a consanguineous marriage, consulted for melanoderma, with family history: sisters with an heterozygous mutation of the AAAS gene, two paternal cousins, 5 years and 22 years, followed for autism an...

Introduction: Early diagnosis is therefore important for patients with asymptomatic diabetes mellitus. The aim of this study is to validate the use of Urine Dipstick in the screening of glycosuria (Gu).Material and methods: Our study involved 30 fresh urine specimens. Urinalysis was performed by dipstick (SPINREAT®). Gu was measured by the hexokinase method (DxC800® Beckman Coulter). The gold standard to diagnose Gu was co...

Introduction: Inappropriate laboratory test utilization can result in unnecessary patient testing and increased healthcare costs. Thyroid-stimulating hormone (TSH) is recommended as the first-line test for investigating and monitoring thyroid dysfunction. We evaluate Thyroid function tests (TFTs) ordering in our hospital practice.Methods: A retrospective descriptive study included 400 TFTs requests. TFTs of interest were: TSH and FT4. These tests request...

Background/Aim: Since diabetes is the most common endocrine disorder and the diabetic ketoacidosis (DKA) is considered as a medical emergency, our aim was to determinate the frequency of symptoms and precipitating factors of DKA in type 1 and type 2 diabetesMethods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrinology Department for DKA between August 2021 to December 2022. We compared the di...

Background/Aim: Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes. Our aim was to study the clinical features of DKA and precipitating factors responsible for DKA in diabetic patients.Methods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrinology Department for DKA between August 2021 and December 2021. Initial kalemia levels (k +) on presentation were determinat...

Introduction: Diabetic ketoacidosis (DKA) is an extreme metabolic state caused by insulin deficiency. Hypophosphatemia in DKA often occurs during hospitalization. The aim of this study was to determine the prevalence and determinants of hypophosphatemia during the treatment of diabetic ketoacidosis.Methods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrinology Department for DKA between Octobe...

Background/Aims: Ketosis in patients with known Type 2 diabetes mellitus is overlooked due to atypical symptoms. Type 2 diabetes (DT2) is characterized by a longer period of asymptomatic hyperglycaemia than Type 1 diabetes(DT1). The objective of this study was to compare glycosylated haemoglobin (HbA1c) levels in ketoacidosis (DKA) occurring in known and newly diagnosed diabetes.Methods: This is a retrospective cross-sectional descriptive study concernin...